E-AB-19799
KLF1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19799
- Zusätzliche Namen:
- CDAN4,EKLF,EKLF PEN,Erythroid Kruppel like factor,Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor),Erythroid krueppel-like transcription factor,Erythroid specific transcription factor EKLF,HBFQTL6,Human erythroid-specif
- Anwendung:
- IHC
- Konzentration:
- 0.96 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human KLF1
- Uniprot:
- Q13351
- Synonyme:
- EKLF;EKLF/KLF1;erythroid krueppel-like transcription factor;erythroid Kruppel-like factor;erythroid-specific transcription factor EKLF;Krueppel-like factor 1;truncated erythroid Kruppel-like factor EKLF/KLF1;truncated Kruppel-like factor 1
- Weitere Details:
- This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
- Versandbedingungen:
- Blue Ice