E-AB-19784
HIST1H2BA Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19784
- Zusätzliche Namen:
- (testis specific),H2B,H2B histone family,H2B histone family member U,H2B histone family member U testis specific,H2B testis,H2B1A,H2BFU,H2BT,H2ba,HIST1H2BA,Histone 1,Histone H2B,Histone H2B testi,Histone cluster 1 H2ba,bA317E16.3,member U,testis
- Anwendung:
- IHC, WB
- Konzentration:
- 1.98 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human HIST1H2BA
- Uniprot:
- Q96A08
- Synonyme:
- bA317E16.3;H2B histone family, member U, (testis-specific);H2BFU;HIST1H2BA;histone 1, H2ba;histone cluster 1 H2B family member a;histone cluster 1, H2ba;histone H2B type 1-A;histone H2B, testis;hTSH2B;STBP;testis-specific histone H2B;TH2B;TSH2B;TSH2B.1
- Weitere Details:
- The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
- Versandbedingungen:
- Blue Ice