ERCC1 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-19768
Zusätzliche Namen:: COFS 4,COFS4,DNA excision repair protein ERCC 1,DNA excision repair protein ERCC-1,DNA excision repair protein ERCC1,ERCC 1,ERCC1,Excision Repair Cross Complementing,Excision repair cross complementation group 1,Excision repair cross complementing 1
Anwendung:: WB
Konzentration:: 1.1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human ERCC1
Uniprot:: P07992
Synonyme:: COFS4;DNA excision repair protein ERCC-1;excision repair cross-complementation group 1;excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence);RAD10;UV20
Weitere Details:: Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11,XPF and ERCC4,which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1,together with RRM1,are determinants of survival after surgical treatment of early-stage,non-small-cell lung cancer. (Ref: Simon,ER. 2005)