E-AB-19512
IRF5 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19512
- Zusätzliche Namen:
- IRF 5,IRF-5,IRF5,Interferon regulatory factor 5,Interferon regulatory factor 5 bone marrow variant,Irf5,SLEB10
- Anwendung:
- IHC, WB
- Konzentration:
- 0.7 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human IRF5
- Uniprot:
- Q13568
- Synonyme:
- interferon regulatory factor 5;SLEB10
- Weitere Details:
- IRF5,also named as SLEB10,contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10).
- Versandbedingungen:
- Blue Ice