E-AB-19459
GLI1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19459
- Zusätzliche Namen:
- GLI,GLI Kruppel family member 1,GLI family zinc finger 1,GLI1,Gli 1,Glioma associated oncogene 1,Glioma associated oncogene homolog,Glioma associated oncogene homolog 1 (zinc finger protein),Glioma-associated oncogene,Oncogene GLI,Zfp 5,Zfp5,Zinc fin,gli1
- Anwendung:
- IHC, WB
- Konzentration:
- 1.08 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human GLI1
- Uniprot:
- P08151
- Synonyme:
- GLI;GLI-Kruppel family member GLI1;Glioma-associated oncogene;glioma-associated oncogene 1;glioma-associated oncogene homolog 1 (zinc finger protein);oncogene GLI;PAPA8;PPD1;zinc finger protein GLI1
- Weitere Details:
- GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice