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E-AB-19288

PPBP Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-19288
Zusätzliche Namen:
B TG1,Beta TG,Beta thromboglobulin,Beta-TG,C-X-C motif chemokine 7,CTAP 3,CTAP III,CTAP-III,CTAP-III(1-81),CTAP3,CTAPIII,CXC chemokine ligand 7,CXCL 7,CXCL7,Chemokine (C X C motif) ligand 7,Connective tissue activating peptide III,LA PF 4,LA-PF4,LDG
Anwendung:
IHC, WB
Konzentration:
0.8 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human PPBP
Uniprot:
P02775
Synonyme:
B-TG1;Beta-TG;beta-thromboglobulin;C-X-C motif chemokine 7;chemokine (C-X-C motif) ligand 7;connective tissue-activating peptide III;CTAP-III;CTAP3;CTAPIII;CXC chemokine ligand 7;CXCL7;LA-PF4;LDGF;leukocyte-derived growth factor;low-affinity platelet factor IV;macrophage-derived growth factor;MDGF;NAP-2;neutrophil-activating peptide 2;PBP;platelet basic protein;SCYB7;small inducible cytokine B7;small inducible cytokine subfamily B, member 7;Small-inducible cytokine B7;TC1;TC2;TGB;TGB1;THBGB;THBGB1;thrombocidin 1;thrombocidin 2;thromboglobulin, beta-1
Weitere Details:
PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Colloid Adenoma. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. GO annotations related to this gene include growth factor activity and glucose transmembrane transporter activity. An important paralog of this gene is CXCL1. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.
Versandbedingungen:
Blue Ice