E-AB-19259
HSD3B2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19259
- Zusätzliche Namen:
- 3 Beta- And Steroid Delta-Isomerase 2, Member 2,3 Bet,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II,3-Beta-HSD Adrenal And Gonadal Type,3-Beta-HSD II,Hydroxy-Delta-5-Steroid Dehydrogenase,Short Chain Dehydrogenase/Reductase Family 11E
- Anwendung:
- WB
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human HSD3B2
- Uniprot:
- P26439
- Synonyme:
- 3 beta-HSD type II;3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II;3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2;3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II;3-beta-HSD adrenal and gonadal type;3-beta-HSD II;3-beta-hydroxy-5-ene steroid dehydrogenase;3-beta-hydroxy-Delta(5)-steroid dehydrogenase;delta 5-delta 4-isomerase type II;HSD3B;HSDB;progesterone reductase;SDR11E2;short chain dehydrogenase/reductase family 11E, member 2
- Weitere Details:
- The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
- Versandbedingungen:
- Blue Ice