E-AB-19200
KCNIP3 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19200
- Zusätzliche Namen:
- 4933407H12Rik,A type potassium channel modulatory protein 3,A-type potassium channel modulatory protein 3,AI413860,CSEN,Calsenilin,DRE antagonist modulator,DRE-antagonist modulator,DREAM,EF hand transcription factor,KCHIP 3,KCNIP 3,KChIP3,Kcnip3,Kv c
- Anwendung:
- IHC
- Konzentration:
- 1.62 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human KCNIP3
- Uniprot:
- Q9Y2W7
- Synonyme:
- A-type potassium channel modulatory protein 3;calsenilin;calsenilin, presenilin-binding protein, EF hand transcription factor;CSEN;DRE-antagonist modulator;DREAM;KCHIP3;Kv channel interacting protein 3, calsenilin;kv channel-interacting protein 3;potassium channel interacting protein 3
- Weitere Details:
- This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.
- Versandbedingungen:
- Blue Ice