E-AB-19116
FAM107B Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19116
- Zusätzliche Namen:
- member B,C10orf45,F107B,FAM107B,FLJ45505,Family with sequence similarity 107,MGC11034,Protein FAM107B
- Anwendung:
- IHC
- Konzentration:
- 1.32 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human FAM107B
- Uniprot:
- Q9H098
- Synonyme:
- C10orf45;FAM107B/CDNF fusion;heat shock-inducible tumor small protein;HITS;protein FAM107B
- Weitere Details:
- FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.
- Versandbedingungen:
- Blue Ice