E-AB-19103
ELOC Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-19103
- Zusätzliche Namen:
- Elongin C), Polypeptide 1 (15kDa,Elongin 15 KDa Subunit,Elongin C,RNA Polymerase II Transcription Factor SIII Subunit C,S,Transcription Elongation Factor B (SIII),Transcription Elongation Factor B Polypeptide 1,Transcription Elongation Factor B Subunit 1
- Anwendung:
- IHC
- Konzentration:
- 0.96 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ELOC
- Uniprot:
- Q15369
- Synonyme:
- elongin 15 kDa subunit;elongin-C;RNA polymerase II transcription factor SIII subunit C;SIII;SIII p15;TCEB1;transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C);transcription elongation factor B polypeptide 1;transcription elongation factor B subunit 1
- Weitere Details:
- This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
- Versandbedingungen:
- Blue Ice