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E-AB-18994

SETMAR Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-18994
Zusätzliche Namen:
Histone lysine N methyltransferase,Histone lysine N methyltransferase SETMAR,Hsmar 1,Hsmar1,Mariner transposase Hsmar1,Metnase,SET domain and mariner transposase fusi,SET domain and mariner transposase fusion,SET domain and mariner transposase fusion gene
Anwendung:
IHC
Konzentration:
1.08 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Fusion protein of human SETMAR
Uniprot:
Q53H47
Synonyme:
histone-lysine N-methyltransferase SETMAR;Mar1;METNASE;SET domain and mariner transposase fusion gene-containing protein;SET domain and mariner transposase fusion protein
Weitere Details:
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Versandbedingungen:
Blue Ice