E-AB-18894
GSKIP Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18894
- Zusätzliche Namen:
- C14ORF129,Chromosome 14 open reading frame 129 ,GSK3-beta interaction protein,GSK3beta interaction protein,GSKIP,MGC4945,UPF0279
- Anwendung:
- IHC
- Konzentration:
- 0.96 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human GSKIP
- Uniprot:
- Q9P0R6
- Synonyme:
- C14orf129;GSK3-beta interaction protein;GSK3B-interacting protein;GSK3beta interaction protein;HSPC210
- Weitere Details:
- This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
- Versandbedingungen:
- Blue Ice