E-AB-18890
IFITM2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18890
- Zusätzliche Namen:
- 1 8D,DSPA2c,Dispanin subfamily A member 2c,IFITM 2,Interferon induced transmembrane protein 2,Interferon induced transmembrane protein 2 (1 8D),Interferon inducible protein 1 8D
- Anwendung:
- IHC
- Konzentration:
- 0.72 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human IFITM2
- Uniprot:
- Q01629
- Synonyme:
- 1-8D;dispanin subfamily A member 2c;DSPA2c;interferon-induced transmembrane protein 2;interferon-inducible protein 1-8D
- Weitere Details:
- IFITM2,also named as 1-8D,belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus (WNV),by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2.
- Versandbedingungen:
- Blue Ice