E-AB-18889
BEX2 Polyclonal Antibody

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£106.20
War £118.00
- SKU:
- E-AB-18889
- Zusätzliche Namen:
- BEX1,DJ79P11.1,HBex2,Protein BEX2
- Anwendung:
- IHC
- Konzentration:
- 0.78 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human BEX2
- Uniprot:
- Q9BXY8
- Synonyme:
- BEX1;brain-expressed X-linked protein 2;DJ79P11.1;hBex2;protein BEX2
- Weitere Details:
- This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice