EXD2 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-18841
Zusätzliche Namen:: 4930539P14Rik,C14orf114,C85658,DKFZp781A0133,DKFZp781L15100,EXD2,EXDL2,Exd2,Exonuclease 3''-5'' domain-containing protein 2,Exonuclease 3''-5'' domain-like-containing protein 2,FLJ10738,RGD1311087,exonuclease 3'-5' domain-like 2
Anwendung:: IHC, WB
Konzentration:: 0.96 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Fusion protein of human EXD2
Uniprot:: Q9NVH0
Synonyme:: 3'-5' exoribonuclease EXD2;C14orf114;EXDL2;exonuclease 3'-5' domain-containing protein 2;exonuclease 3'-5' domain-like 2;exonuclease 3'-5' domain-like-containing protein 2
Weitere Details:: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.