E-AB-18828
ADRM1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18828
- Zusätzliche Namen:
- 000 surface antigen,110 kDa cell membrane glycoprotein,ADRM 1,ADRM1,ARM 1,ARM-1,ARM1,Adhesion-regulating molecule 1,Adrm1,Gp110,M(r) 110,Proteasomal ubiquitin receptor ADRM1,adhesion regulating molecule 1,hRpn13,proteasome regulatory particle non ATPase 1
- Anwendung:
- IHC
- Konzentration:
- 1.26 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ADRM1
- Uniprot:
- Q16186
- Synonyme:
- 110 kDa cell membrane glycoprotein;adhesion regulating molecule 1;Adhesion-regulating molecule 1;ARM-1;ARM1;GP110;M(r) 110,000 surface antigen;proteasomal ubiquitin receptor ADRM1;proteasome regulatory particle non-ATPase 13;proteasome ubiquitin receptor;PSMD16;rpn13 homolog
- Weitere Details:
- The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
- Versandbedingungen:
- Blue Ice