E-AB-18676
UBXN1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18676
- Zusätzliche Namen:
- 2B28,4930455J02Rik,D19Ertd721e,MGC124706,MGC6696,Protein 2B28,RGD1309471,SAKS1,SAPK substrate protein 1,T25529,UBA/UBX 33.3 kDa protein,UBX domain containing protein 1,UBX domain protein 1,UBXD10,UBXN1,mY33K
- Anwendung:
- IHC, WB
- Konzentration:
- 1.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Full length fusion protein
- Uniprot:
- Q04323
- Synonyme:
- 2B28;SAKS1;SAPK substrate protein 1;UBA/UBX 33.3 kDa protein;UBX domain-containing protein 1;UBXD10
- Weitere Details:
- Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
- Versandbedingungen:
- Blue Ice