E-AB-18538
PHF21A Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18538
- Zusätzliche Namen:
- BHC80a,BM-006,BRAF35-HDAC complex protein BHC80,BRAF35/HDAC2 complex (80 kDa),KIAA1696,PF21A,PHD finger protein 21A,PHF21A
- Anwendung:
- IHC, WB
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human PHF21A
- Uniprot:
- Q96BD5
- Synonyme:
- BHC80;BHC80a;BM-006;BRAF35-HDAC complex protein BHC80;BRAF35/HDAC2 complex (80 kDa);IDDBCS;NEDMS;PHD finger protein 21A
- Weitere Details:
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
- Versandbedingungen:
- Blue Ice