E-AB-18439
PRNP Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18439
- Zusätzliche Namen:
- major prion protein,ASCR,AltPrP,Alternative prion protein,CD230,CD230 antigen,CJD,GSS,KURU,Major prion protein,PRIO,PRIP,PRNP,PrP,PrP27 30 ,PrP27-30,PrP33-35C,PrPC,PrPSc,Prion protein,Prion related protein,Sinc,p27 30
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human PRNP
- Uniprot:
- P04156
- Synonyme:
- alternative prion protein;AltPrP;ASCR;CD230;CD230 antigen;CJD;GSS;KURU;major prion protein;p27-30;prion-related protein;PRIP;PrP;PrP27-30;PrP33-35C;PrPc
- Weitere Details:
- The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice