E-AB-18330
ATF6B Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-18330
- Zusätzliche Namen:
- ATF6-beta,ATF6B,Activating transcription factor 6 beta,CREBL1,Cyclic AMP-dependent transcription factor ATF-6 beta,G13,Protein G13,cAMP response element-binding protein-related protein,cAMP-dependent transcription factor ATF-6 beta
- Anwendung:
- IHC, WB
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ATF6B
- Uniprot:
- Q99941
- Synonyme:
- Activating transcription factor 6 beta;cAMP response element-binding protein-related protein;cAMP-dependent transcription factor ATF-6 beta;cAMP-responsive element-binding protein-like 1;Creb-related protein;CREB-RP;CREBL1;cyclic AMP-dependent transcription factor ATF-6 beta;G13;protein G13
- Weitere Details:
- The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice