E-AB-17927
HLA-DRA Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-17927
- Zusätzliche Namen:
- DR alpha chain,DR alpha chain precursor,DRA,DRB1,DRB4,HLA ,HLA DR1B,HLA DR3B,HLA DRA,HLA DRA1,HLA DRB1,HLA DRB3,HLA DRB4,HLA class II histocompatibility antigen,HLA class II histocompatibility antigen DR alpha chain,Histocompatibility antigen HLA DR alpha
- Anwendung:
- IHC
- Konzentration:
- 0.9 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human HLA-DRA
- Uniprot:
- P01903
- Synonyme:
- histocompatibility antigen HLA-DR alpha;HLA class II histocompatibility antigen, DR alpha chain;HLA-DRA1;MHC class II antigen DRA
- Weitere Details:
- HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
- Versandbedingungen:
- Blue Ice