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IL17A Polyclonal Antibody

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E-AB-17917

IL17A Polyclonal Antibody

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£106.20

War £118.00

SKU:
E-AB-17917
Zusätzliche Namen:
Cytotoxic T-lymphocyte-associated antigen,IL17A,CTLA-8,CTLA8,IL-17,IL-17A,IL17,Interleukin-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA 8,CTLA8,CTLA-8,CTLA8cytotoxic T-lymphocyte-associated serine esterase 8,Cytotoxic T-lymphocyte-associated antigen 8,IL17,IL-17,IL17A,IL-17A,IL-17Acytotoxic T-lymphocyte-associated protein 8,IL-17CTLA-8,Cytotoxic T lymphocyte associated antigen 8,Cytotoxic T lymphocyte associated protein 8,Cytotoxic T lymphocyte associated serine esterase 8,IL
Anwendung:
IHC
Konzentration:
1.14 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human IL17A
Uniprot:
Q16552
Synonyme:
CTLA-8;CTLA8;cytotoxic T-lymphocyte-associated antigen 8;cytotoxic T-lymphocyte-associated protein 8;IL-17;IL-17A;IL17;ILA17;interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8);interleukin-17;interleukin-17A
Weitere Details:
IL17A,also named as IL-17,is a proinflammatory cytokine. IL-17,synthesized only by memory T cells and natural killer cells,has pleiotropic effects,mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2),as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis,psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein,that is widely expressed on epithelial cells,fibroblasts,B and T cells,and monocytic cells. In psoriatic skin lesions,both Th17 cells and their downstream effector molecules,e.g. IL-17 and IL-22,are highly increased.
Versandbedingungen:
Blue Ice