E-AB-17889
DMGDH Polyclonal Antibody
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£106.20
War £118.00
- SKU:
- E-AB-17889
- Zusätzliche Namen:
- Dimethylglycine dehydrogenase,Dmgdh,M2GD,ME2GLYDH,mitochondrial
- Anwendung:
- WB
- Konzentration:
- 2.1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human DMGDH
- Uniprot:
- Q9UI17
- Synonyme:
- dimethylglycine dehydrogenase, mitochondrial;DMGDHD;ME2GLYDH
- Weitere Details:
- This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice