E-AB-17341
INHBB Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-17341
- Zusätzliche Namen:
- Activin beta B chain,Activin beta-B chain,INHBB,Inhibin beta 2,Inhibin beta B chain,Inhibin beta B subunit
- Anwendung:
- IHC
- Konzentration:
- 0.8 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human INHBB
- Uniprot:
- P09529
- Synonyme:
- activin AB beta polypeptide;activin beta-B chain;inhibin beta B chain;inhibin beta B subunit;Inhibin, beta-2
- Weitere Details:
- The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
- Versandbedingungen:
- Blue Ice