E-AB-17184
UACA Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-17184
- Zusätzliche Namen:
- FLJ10128,KIAA1561,MGC141967,MGC141969,NUCLING,Nuclear membrane binding protein,UACA,Uveal autoantigen with coiled coil domains and ankyrin repeats,Uveal autoantigen with coiled-coil domains and ankyrin repeats
- Anwendung:
- IHC
- Konzentration:
- 0.8 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human UACA
- Uniprot:
- Q9BZF9
- Synonyme:
- nuclear membrane binding protein;NUCLING;uveal autoantigen with coiled-coil domains and ankyrin repeats
- Weitere Details:
- Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
- Versandbedingungen:
- Blue Ice