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E-AB-16872

ROR1 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-16872
Zusätzliche Namen:
Inactive tyrosine protein kinase transmembrane receptor ROR1,MGC99659,NTRKR1,Neurotrophic tyrosine kinase,Neurotrophic tyrosine kinase receptor related 1,OTTHUMP00000010573,OTTHUMP00000010574,OTTM,dJ537F10.1,receptor related 1
Anwendung:
IHC
Konzentration:
0.5 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ROR1
Uniprot:
Q01973
Synonyme:
dJ537F10.1;inactive tyrosine-protein kinase transmembrane receptor ROR1;neurotrophic tyrosine kinase, receptor-related 1;NTRKR1
Weitere Details:
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Versandbedingungen:
Blue Ice