E-AB-16703
PERK Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-16703
- Zusätzliche Namen:
- DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,HRI,Heme regulated EIF2 alpha kinase,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinas
- Anwendung:
- IHC
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human EIF2AK3
- Uniprot:
- Q9NZJ5
- Synonyme:
- eukaryotic translation initiation factor 2-alpha kinase 3;pancreatic EIF2-alpha kinase;PEK;PERK;PRKR-like endoplasmic reticulum kinase;truncated eukaryotic translation initiation factor 2 alpha kinase 3;WRS
- Weitere Details:
- The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis.It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins.Mutations in this gene are associated with Wolcott-Rallison syndrome.
- Versandbedingungen:
- Blue Ice