MRGPRX1 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-16618
Zusätzliche Namen:: GPCR,MAS related GPR member X1,MAS related gene MRGX1,MRGPRX1,MRGX1,SNSR4
Anwendung:: IHC
Konzentration:: 0.5 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human MRGPRX1
Uniprot:: Q96LB2
Synonyme:: G protein-coupled receptor MRGX1;G protein-coupled receptor SNSR3;GPCR;Mas-related G protein-coupled receptor G2;mas-related G-protein coupled receptor member X1;MAS-related GPR, member X1;MGRG2;MRGX1;sensory neuron-specific G-protein coupled receptor 3/4;SNSR4
Weitere Details:: MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.