E-AB-16525
ITGB7 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-16525
- Zusätzliche Namen:
- Gut homing receptor beta subunit,ITB7,Integrin,Integrin beta 7 subunit,Integrin beta-7,Integrin beta-P,Itgb7,Ly69,M290 IEL antigen,beta 7
- Anwendung:
- IHC
- Konzentration:
- 0.7 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ITGB7
- Uniprot:
- P26010
- Synonyme:
- gut homing receptor beta subunit;integrin beta 7 subunit;integrin beta-7
- Weitere Details:
- This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
- Versandbedingungen:
- Blue Ice