E-AB-16507
IGF2R Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-16507
- Zusätzliche Namen:
- 300 kDa mannose 6 phosphate receptor,300 kDa mannose 6-phosphate receptor,CD222,CD222 antigen,CI MPR,CI Man 6 P receptor,CI Man-6-P receptor,CI-M6PR,CI-MPR,CIM,Cation independent mannose 6 phosphate receptor,Cation-independent mannose-6-phosphate receptor
- Anwendung:
- IHC
- Konzentration:
- 0.4 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human IGF2R
- Uniprot:
- P11717
- Synonyme:
- 300 kDa mannose 6-phosphate receptor;cation-independent mannose-6-phosphate receptor;CD222;CI Man-6-P receptor;CI-M6PR;CIMPR;IGF-II receptor;Insulin-like growth factor 2 receptor;insulin-like growth factor II receptor;M6P-R;M6P/IGF2 receptor;M6P/IGF2R;MPR 300;MPR1;MPR300;MPRI
- Weitere Details:
- This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
- Versandbedingungen:
- Blue Ice