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E-AB-16196

DDAH1 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-16196
Zusätzliche Namen:
DDAH,DDAH I,DDAH-1,DDAH1,DDAHI,Dimethylargininase 1,Dimethylargininase-1,Dimethylarginine dimethylaminohydrolase 1,N(G),N(G)-dimethylarginine dimethylaminohydrolase 1,NG NG dimethylarginine dimethylaminohydrolase
Anwendung:
IHC
Konzentration:
0.2 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human DDAH1
Uniprot:
O94760
Synonyme:
DDAH;DDAH-1;DDAHI;dimethylargininase-1;epididymis secretory protein Li 16;HEL-S-16;N(G),N(G)-dimethylarginine dimethylaminohydrolase 1;NG, NG-dimethylarginine dimethylaminohydrolase
Weitere Details:
This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Versandbedingungen:
Blue Ice