E-AB-15992
CD10 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15992
- Zusätzliche Namen:
- Atriopeptidase,CALLA,CD10,CD10 antigen,Common acute lymphocytic leukemia antigen,DKFZp686O16152,EC 3.4.24.11,EPN,Enkephalinase,Membrane metallo endopeptidase (neutral endopeptidase,enkep,enkephalinase)
- Anwendung:
- IHC
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human MME
- Uniprot:
- P08473
- Synonyme:
- atriopeptidase;CALLA;CD10;CMT2T;common acute lymphocytic leukemia antigen;Enkephalinase;membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10);membrane metallo-endopeptidase variant 1;membrane metallo-endopeptidase variant 2;NEP;neprilysin;neprilysin-390;neprilysin-411;neutral endopeptidase 24.11;SCA43;SFE;skin fibroblast elastase
- Weitere Details:
- This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL).This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb.The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.The coding region is not affected by alternative splicing.
- Versandbedingungen:
- Blue Ice