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E-AB-15973

DDR2 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-15973
Zusätzliche Namen:
CD167 antigen-like family member B,CD167b,CD167b antigen,Cell migration inducing protein 20,DDR 2,DDR2,Discoidin domain containing receptor 2,Discoidin domain receptor 2,Discoidin domain receptor family member 2,discoidin domain receptor tyrosine ki
Anwendung:
IHC
Konzentration:
0.4 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human DDR2
Uniprot:
Q16832
Synonyme:
CD167 antigen-like family member B;cell migration-inducing protein 20;discoidin domain receptor 2;discoidin domain receptor family, member 2;discoidin domain-containing receptor 2;discoidin domain-containing receptor tyrosine kinase 2;hydroxyaryl-protein kinase;MIG20a;migration-inducing gene 16 protein;neurotrophic tyrosine kinase receptor related 3;Neurotrophic tyrosine kinase, receptor-related 3;NTRKR3;receptor protein-tyrosine kinase TKT;TKT;TYRO10;tyrosine-protein kinase TYRO10;WRCN
Weitere Details:
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment.These molecules are involved in the regulation of cell growth, differentiation, and metabolism.In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation.This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction.RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions.This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain.
Versandbedingungen:
Blue Ice