NCOR1 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-15800
Zusätzliche Namen:: KIAA1047,N CoR,N CoR1,N Cor/SMRT corepressor Rip13,N-CoR,N-CoR1,NCOR 1,NCOR1,NCoR,Ncor1,Nuclear receptor co repressor 1,Nuclear receptor corepressor 1,RIP13,Retinoid X receptor interacting protein 13,Rxrip13,hN CoR,hNCoR,thyroid hormone and retinoic acid
Anwendung:: IHC
Konzentration:: 0.6 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human NCOR1
Uniprot:: O75376
Synonyme:: hN-CoR;N-CoR;N-CoR1;nuclear receptor corepressor 1;PPP1R109;protein phosphatase 1, regulatory subunit 109;thyroid hormone- and retinoic acid receptor-associated corepressor 1;TRAC1
Weitere Details:: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.