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E-AB-15798

NBN Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-15798
Zusätzliche Namen:
AT V1,AT V2,ATV,Cell cycle regulatory protein p95,FLJ10155,MGC87362,NBN,NBS,NBS 1,NBS1,Nbn,Nibrin,Nijmegen breakage syndrome,Nijmegen breakage syndrome 1 (nibrin),Nijmegen breakage syndrome protein 1,p95,p95 protein of the MRE11/RAD50 complex
Anwendung:
IHC
Konzentration:
0.5 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human NBN
Uniprot:
O60934
Synonyme:
AT-V1;AT-V2;ATV;cell cycle regulatory protein p95;NBS;NBS1;nibrin;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome protein 1;P95;p95 protein of the MRE11/RAD50 complex
Weitere Details:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Versandbedingungen:
Blue Ice