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E-AB-15703

GRK2 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-15703
Zusätzliche Namen:
ADRBK1,ARBK1,Adrenergic beta receptor kinase 1,BARK,BARK1,Beta ARK 1,Beta ARK1,Beta adrenergic receptor kinase 1,Beta-ARK-1,Beta-adrenergic receptor kinase 1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
Anwendung:
IHC
Konzentration:
0.5 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human ADRBK1
Uniprot:
P25098
Synonyme:
ADRBK1;adrenergic beta receptor kinase 1;BARK1;beta-adrenergic receptor kinase 1;beta-ARK-1;BETA-ARK1;G-protein coupled receptor kinase 2
Weitere Details:
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Versandbedingungen:
Blue Ice