E-AB-15661
GAD2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15661
- Zusätzliche Namen:
- 65 kDa glutamic acid decarboxylase,DCE 2,DCE2,GAD 2,GAD 65,GAD-2,GAD-65,Gad2,Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa),Glutamate Decarboxylase 65,Glutamate decarboxyla,Glutamate decarboxylase 2,Glutamate decarboxylase 2 (pancreas)
- Anwendung:
- IHC
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human GAD2
- Uniprot:
- Q05329
- Synonyme:
- 65 kDa glutamic acid decarboxylase;GAD-65;GAD65;glutamate decarboxylase 2;glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa);Glutamate decarboxylase 65 kDa isoform;Glutamate decarboxylase-2 (pancreas)
- Weitere Details:
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
- Versandbedingungen:
- Blue Ice