E-AB-15650
FOXL2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15650
- Zusätzliche Namen:
- BPES,BPES 1,BPES1,Blepharophimosis,Blepharophimosis epicanthus inversus and ptosis,Blepharophimosis epicanthus inversus and ptosis 1,Epicanthus inversus and ptosis 1,FOX L2,FOXL 2,Forkhead box L2,Forkhead box protein L2,Forkhead transcription factor FOXL2
- Anwendung:
- WB
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human FOXL2
- Uniprot:
- P58012
- Synonyme:
- BPES;BPES1;forkhead box protein L2;forkhead transcription factor FOXL2;PFRK;PINTO;POF3
- Weitere Details:
- This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
- Versandbedingungen:
- Blue Ice