E-AB-15624
ER alpha Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15624
- Zusätzliche Namen:
- 4,5,6,7*,7*/822 isoform,8*/941 isof,DKFZp686N23123,ER,ER alpha,ER-alpha,ESR,ESR1,ESRA,Era,Estradiol receptor,Estrogen nuclear receptor alpha,Estrogen receptor 1,Estrogen receptor alpha,Estrogen receptor alpha 3*,Estrogen receptor alpha delta 3*
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ESR1
- Uniprot:
- P03372
- Synonyme:
- E2 receptor alpha;ER;ER-alpha;Era;ESR;ESRA;estradiol receptor;estrogen nuclear receptor alpha;estrogen receptor;estrogen receptor alpha E1-E2-1-2;estrogen receptor alpha E1-N2-E2-1-2;ESTRR;NR3A1;nuclear receptor subfamily 3 group A member 1;oestrogen receptor alpha
- Weitere Details:
- This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
- Versandbedingungen:
- Blue Ice