E-AB-15623
EPOR Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15623
- Zusätzliche Namen:
- EPO R,EPO-R,EPOR,Erythropoietin receptor,Erythropoietin receptor precursor,MGC138358,epor
- Anwendung:
- IHC
- Konzentration:
- 0.7 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human EPOR
- Uniprot:
- P19235
- Synonyme:
- EPO-R;erythropoietin receptor;truncated erythropoietin receptor
- Weitere Details:
- This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice