E-AB-15620
EPCAM Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15620
- Zusätzliche Namen:
- 17 1A,323/A3,AUA1,Adenocarcinoma associated antigen,Adenocarcinoma-associated antigen,Antigen identified by monoclonal AUA1,CD326,CD326 antigen,CO 17A,CO17 ,Cell surface glycoprotein Trop 1,Cell surface glycoprotein Trop 2,Cell surface glycoprotein Trop-1
- Anwendung:
- IHC
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human EPCAM
- Uniprot:
- P16422
- Synonyme:
- adenocarcinoma-associated antigen;cell surface glycoprotein Trop-1;DIAR5;EGP-2;EGP314;EGP40;epithelial cell adhesion molecule;Epithelial cell surface antigen;Epithelial glycoprotein;epithelial glycoprotein 314;ESA;HNPCC8;human epithelial glycoprotein-2;KS 1/4 antigen;KS1/4;KSA;M4S1;major gastrointestinal tumor-associated protein GA733-2;membrane component, chromosome 4, surface marker (35kD glycoprotein);MIC18;MK-1;TACSTD1;TROP1;trophoblast cell surface antigen 1;tumor-associated calcium signal transducer 1
- Weitere Details:
- This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas. It is expressed in undifferentiated pluripotent stem cells.tufting enteropathy.
- Versandbedingungen:
- Blue Ice