NECTIN1 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-15611
Zusätzliche Namen:: CD111,CD111 antigen,CLPED1,ED4,HIgR,Herpes virus entry mediator C,Herpesvirus Ig like receptor,Herpesvirus Ig-like receptor,Herpesvirus entry mediator C,HveC,MGC142031,Nectin 1,Nectin-1,OFC7,OROFACIAL CLEFT 7,ectodermal dysplasia 4 (Margarita Island type)
Anwendung:: WB
Konzentration:: 0.3 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human PVRL1
Uniprot:: Q15223
Synonyme:: CD111;CLPED1;ectodermal dysplasia 4 (Margarita Island type);ED4;herpes simplex virus type 1 sensitivity;herpes virus entry mediator C;herpesvirus Ig-like receptor;HIgR;HV1S;HVEC;nectin 1;Nectin cell adhesion molecule 1;nectin-1;OFC7;poliovirus receptor-like 1;poliovirus receptor-related 1 (herpesvirus entry mediator C);poliovirus receptor-related protein 1;PRR;PRR1;PVRL1;PVRR;PVRR1;SK-12
Weitere Details:: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Versandbedingungen:: Blue Ice