E-AB-15178
LRRC15 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15178
- Zusätzliche Namen:
- LIB,LRC15,LRRC15,Leucine-rich repeat protein induced by beta-amyloid homolog,Leucine-rich repeat-containing protein 15,hLib
- Anwendung:
- IHC
- Konzentration:
- 0.9 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human LRRC15
- Uniprot:
- Q8TF66
- Synonyme:
- hLib;leucine-rich repeat protein induced by beta amyloid;leucine-rich repeat protein induced by beta-amyloid homolog;leucine-rich repeat-containing protein 15;LIB
- Weitere Details:
- Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.
- Versandbedingungen:
- Blue Ice