LDOC1 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-15168
Zusätzliche Namen:: BCUR1,Breast cancer up regulated 1,Breast cancer upregulated 1,Gm366,LDOC1,Ldoc1,Leucine zipper down regulated in cancer 1,Leucine zipper protein d,Leucine zipper protein down regulated in cancer cells
Anwendung:: IHC
Konzentration:: 0.4 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human LDOC1
Uniprot:: O95751
Synonyme:: BCUR1;breast cancer, up-regulated 1;leucine zipper down-regulated in cancer 1;leucine zipper downregulated in cancer;leucine zipper protein down-regulated in cancer cells;mammalian retrotransposon-derived 7;Mar7;Mart7;protein LDOC1;retrotransposon Gag like 7;RTL7;SIRH7;Sushi-Ichi retrotransposon homolog 7
Weitere Details:: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.