Skip to content

Datenblatt ansehen

open_in_new
  1. Alles ansehen
  2. Polyclonal

E-AB-15154

KCNQ1 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-15154
Zusätzliche Namen:
ATFB1,ATFB3,FLJ26167,IKs producing slow voltage-gated potassium channel subunit alpha,IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1,JLNS1,Jervell and Lange-Nielsen syndrome 1,KCNA8,KCNA9,KCNQ1,kidney and cardiac voltage dep
Anwendung:
IHC, WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human KCNQ1
Uniprot:
P51787
Synonyme:
ATFB1;ATFB3;IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1;JLNS1;KCNA8;KCNA9;kidney and cardiac voltage dependend K+ channel;KQT-like 1;Kv1.9;Kv7.1;KVLQT1;LQT;LQT1;potassium channel, voltage gated KQT-like subfamily Q, member 1;potassium voltage-gated channel subfamily KQT member 1;potassium voltage-gated channel, KQT-like subfamily, member 1;RWS;slow delayed rectifier channel subunit;SQT2;voltage-gated potassium channel subunit Kv7.1;WRS
Weitere Details:
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
Versandbedingungen:
Blue Ice