E-AB-15128
IKBIP Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-15128
- Zusätzliche Namen:
- FLJ31051,I kappa B kinase interacting protein,IKBIP,IKBKB interacting protein,IKIP1,IKIP2,IKIP3,IKK interacting protein,Inhibitor of nuclear factor kappa B kinase interacting protein
- Anwendung:
- IHC
- Konzentration:
- 0.4 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human IKBIP
- Uniprot:
- Q70UQ0
- Synonyme:
- I kappa B kinase interacting protein;i kappa-B kinase-interacting protein;IKIP;IKK interacting protein;inhibitor of nuclear factor kappa-B kinase-interacting protein
- Weitere Details:
- IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
- Versandbedingungen:
- Blue Ice