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E-AB-14947

DLD Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-14947
Zusätzliche Namen:
DLDD,DLDH,Dehydrogenase complex,Diaphorase,Dihydrolipoamide dehydrogenase,Dihydrolipoyl dehydrogenase,Dihydrolipoyl dehydrogenase mitochondrial,E3,E3 branched chain aplha-keto acid,E3 component,E3 component ,E3 component of pyruvate dehydrogenase,dld
Anwendung:
IHC
Konzentration:
0.6 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human DLD
Uniprot:
P09622
Synonyme:
diaphorase;Dihydrolipoamide dehydrogenase;dihydrolipoyl dehydrogenase, mitochondrial;DLDD;DLDH;E3;E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex;epididymis secretory sperm binding protein;GCSL;glycine cleavage system L protein;glycine cleavage system protein L;LAD;lipoamide dehydrogenase;lipoamide reductase;lipoyl dehydrogenase;OGDC-E3;PHE3
Weitere Details:
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.
Versandbedingungen:
Blue Ice