E-AB-14938
DCTN4 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14938
- Zusätzliche Namen:
- DCTN 4,DCTN4,Dctn4,Dynactin 4,Dynactin 4 (p62),Dynactin p62 subunit,Dynactin subunit 4,Dynactin subunit p62,Dynactin4,p62
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human DCTN4
- Uniprot:
- Q9UJW0
- Synonyme:
- DYN4;dynactin 4 (p62);dynactin p62 subunit;dynactin subunit 4;dynactin subunit p62;P62
- Weitere Details:
- Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
- Versandbedingungen:
- Blue Ice