E-AB-14899
RBBP8 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14899
- Zusätzliche Namen:
- COM1,CtBP interacting protein,CtBP-interacting protein,CtIP,DNA endonuclease RBBP8,JWDS,RB binding protein 8 endonuclease,RBBP-8,RBBP8,Retinoblastoma-binding protein 8,Retinoblastoma-interacting protein and myosin-like,Rim,SAE2,SCKL2,Sporulation in t
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human RBBP8
- Uniprot:
- Q99708
- Synonyme:
- COM1;CTBP-interacting protein;CTIP;DNA endonuclease RBBP8;JWDS;RBBP-8;retinoblastoma binding protein 8;Retinoblastoma-binding protein 8;Retinoblastoma-interacting protein and myosin-like;RIM;SAE2;SCKL2;sporulation in the absence of SPO11 protein 2 homolog
- Weitere Details:
- The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
- Versandbedingungen:
- Blue Ice