E-AB-14814
CAST Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14814
- Zusätzliche Namen:
- BS 17,Calpain inhibitor,Calpastatin,Cast,Heart type calpastatin,ICAL,MGC9402,Sperm BS 17 component,Sperm BS-17 component
- Anwendung:
- IHC, WB
- Konzentration:
- 0.7 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CAST
- Uniprot:
- P20810
- Synonyme:
- BS-17;calpain inhibitor;calpastatin;PLACK;sperm BS-17 component
- Weitere Details:
- The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
- Versandbedingungen:
- Blue Ice